The trichomonad belongs to mastigote’s one kind, may divide into according to the parasitic spot: Vagina trichomonad, other trichomonads (person trichomonad, oral cavity trichomonad). The vagina trichomonad is the main parasitism in the feminine vagina, after the vagina the dome sees, may also discover in the urethra; The masculine infected person parasites generally in the urethra, the prostate gland, may also under the testicle, the epididymis or the wrapper parasites, is by the natural dissemination one infectious disease primarily, the global distribution, the crowd infects universally. The vagina trichomonad life history is simple, only has nourishes the body time. The polypite reproduces by the vertical binary fission law, swallows and swallows drinks ingestion food. The polypite is strong in the outside environment viability, has certain resistance poor surroundings ability. Nourishes the body for this insect’s infection time, infects through direct or the mediate contact way.
??The vagina trichomonad’s pathogenicity and the host physiology condition changes along with the insect. In the normal condition, the healthy woman’s vagina environment, maintains because of bacillus lacticus’s function the acidity (pH between 3.8~4.4), may suppress the polypite or other bacterium growth reproduces, this is called vagina’s automatic depuration function. If urogenital system function being out of balance, after like pregnancy, menstruation, causes in the vagina the pH close neutrality, is advantageous in the infusorium and the bacterium growth. But time infusorium parasitism vagina, the consumption glycogen, the hindrance bacillus lacticus’s zymolysis function, has affected the lactic acid density, thus causes vagina’s pH to transform into the neutrality or the alkalinity, the infusorium can reproduce massively, promotes the sequential bacterial infection, the aggravation inflammation response.
??A majority insect pathogenicity is low, although many women have the vagina trichomonad infection, but not clinical symptoms or the symptom are not obvious; Another some insect may cause the obvious vaginitis, the patient vaginal wall obvious mucous membrane hyperemia, dropsy, the epithelial cell denaturation falls off, pathological changes and so on white blood cell infiltration, the light vagina mucous membrane does not have exceptionally discovered. The patient principal claim genitals titillation, the leucorrhea increases. The serious time vulva feels the scalding hot stabbing pain, the sexual intercourse pain, even interferes with the work or the sleep. Examines cloudy when the obvious vagina secretion increases, assumes the yellow, the belt soaks the shape, is accompanied by the stink, also has assumes the cream color the liquidity secretion, when partner bacterial infection the leucorrhea assumes the pus liquidity or the flesh color shape. When infusorium infringement urethra may have frequent micturition, the urgency of urination and the urine painful symptom, sometimes also obvious hematuria. The masculine infected person common symptomless assumes the belt insect condition, may incur spouse’s tandem duplication infection. Sometimes also causes the urethra prostatitis, presents a night of urine to increase, partial tenderness. According to the report, in respiratory infections’ newborn respiratory tract, the tunica conjunctiva oculi discovery vagina trichomonad, possibly is in obtains the infection from time to time through the birth canal. Some scholars thought that the vagina trichomonad can swallow the sperm, the secretion hindrance sperm survival, therefore has the possibility to cause sterility. Also has thought that the carcinoma of cervix and the vagina infusorium infection concerns.
Origin of infection: For infusorium vaginitis patient and symptomless belt insect or masculine infected person.
??Ways of infection: The direct dissemination, mainly disseminates through the sexual intercourse. In the natural opening country, male and female both sides may infect, the prostitute infection percentage is high; The indirect dissemination, mainly through the thermae, the bath gear, the public swimming clothing, the sitting restroom infects, especially in the sanitation facility bad unit, often causes through the toilet popularly. Nourishes the body to be big in the outside environment resistivity, sticks nourishes the body on the restroom board to be possible to survive 30 minutes, in the moist towel, the clothing may survive for 23 hours, 40? Shui Zhongneng lives for 102 hours, 2~3? Shui Zhongke lives for 65 hours, in the ordinary soapy water lives 45~150 minutes, thus in the neglect health, in the civilized bad society easy to infect mutually.
Prevention
??Discovered that symptomless’s belt insect and the patients should diagnose promptly reduce and the control origin of infection, especially husbands and wives both sides must simultaneously use the formula to be able to permanently cure. The commonly used oral administration anti-infusorium medicine for the armor niter zuo (the armor nitryl hydroxy second grade zuo, metronidazole, extinguishes drop zuo) pai the niter sai zuo acetyl shen amine. Armor niter imidazole (metronidazole, partial available drop Uygur only. The vagina maintains the acidic environment effect is good, available 1:5000 Gao Mengsuan potassium fluid flushing vagina. Improves the public utility, the purification public toilet, like changes the tub bath to shower, sits the restroom to change squats the restroom, pays attention to the personal hygiene and the menstrual period health and so on. When meets by chance the anti-armor niter zuo infusorium infection, may consider that changes to the acetyl shen amine to give the medicine partially.
The acetyl shen amine for the pentavalent shen medicinal preparation, its compound prescription preparation calls drop Uygur only. Puts in the vagina dome department by its tablet to have kills the infusorium function directly. This medicine has the mild local excitation function, makes the vagina secretion to increase.
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Armor niter zuo
[pharmacological action] The armor niter zuo (armor niter clip clop zuo, metronidazole, metronidazole, flagyl) can suppress many kinds of protozoan’s redox reactions, causes the pathogen nitrogen chain break, the polypite death.
[clinical practice] Is the Amoebic dysentery, outside the amebic abscess of liver and other intestines amebiasis, treatment and so on infusorium vaginitis, urethritis first choice medicines. May also use in treating Jia Dichong the sickness, the distiller’s grain nose and so on. This medicine also has the anti-anaerobe function.
[untoward effect] This medicine for highly effective low poisonous anti-protozoan medicine, but after certain people take, may have the appetite to drop, disgusting, gastro-intestinal tracts and so on diarrhea, abdominal pain to respond, occasionally sees the headache, losing sleep, the skin rash, the white blood cell reduction and the nervous system symptom and so on, after stopping the medicine, may restore. The pregnancy early time, the breast-feeding period woman, central nervous system disease and the nosohemia patient are forbid.
[preparation and usage] Tablet: Each piece of 200mg; The vagina effervesces the piece: Each piece of 200mg; Suppositories: Each 0.5g,1g; Inoculation fluid: 500mg(10ml),100mg(20ml),1.25 (250ml),500mg(250ml). Armor niter zuo glucose inoculation fluid: Armor niter zuo 0.5g+ glucose 12.5g(250ml).
Treats amebiasis: The adult takes orally each time 400~800mg, daily 3 times, on 5~10th is 1 treatment course. In the vein starts by 15mg/kg, afterward by 7.5mg/kg, every 6~8 hours is redundant 1 time.
Treats trichomoniasis: The adult each time takes 200mg, daily 3 times, moreover, puts in every night the vagina with the 200mg suppositories, is used together on 7~10th, is the guarantee curative effect, must husbands and wives Tongzhi.
Governs Jia Dichong the sickness: Therapeutic dose oral administration each time 400~800mg, the daily 3 times, on 5th are 1 treatment course.
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For niter zuo
For niter zuo (armor sulphur zuo, tinidazole) pharmacological action and clinical practice and armor niter zuo similar, the toxicity is slightly low, the side effect is small, is safe.
The commonly used preparation is: Tablet: Each piece of 0.5g.
Inoculation fluid: Each bottle 400mg(200ml) or 800mg (400ml contains glucose 5.5%).
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Acetyl shen amine
The acetyl shen amine (acetarsol, drops Uygur only, deveganum) has the inhibitory action to the vagina trichomonad and the amoeba protozoan. The existing preparation for the drop Uygur piece, each piece including acetyl shen amine 0.25g, boric acid 0.03g, uses in the infusorium vaginitis’s treatment only. The method to use the thin disinfection fluid (1?5000 potassium permanganate solution) flushes the vagina, then puts the acetyl shen amine 1~2 pieces in the vagina arch department, the inferior early morning sitz bath, by against skin rash, is used together for 10~14 days.
