The Big fish big meat Diet injures cystic kidney
Medicine department university in the Hubei attaches a the internal medicine Doctor of the hospital nephrosis to give birth to a tutor Gu Ru Han the professor display of a research paper point out, high sterone Diet not only will aggravate a nephrosis, the sufferer has already have of the cystic kidney injure, also will cause the healthy person’s kidney is damaged.
They feed to keep big rat with the high sterone animal feed that 4% cholesterols and 1% cholic acid sodiums constitute, build up a high sterone model and carry on a relevant observation and the examination and various experiment study.Discover as a result that give big rat Si the high sterone Diet be 8 turnovers, the big rat namely appears amount of albuminuria to obviously increase, the serum lipid increases Gao, particularly is serum total cholesterol and low density lipoprotein to increase Gao.This confirmation, the high sterone Diet can make healthy kidney damaged.
They study to discover further, Si with high sterone Diet after, along with the go up of serum lipid, the big rat wet an oxidase nitrogen excretion the quantity obviously increase, in the kidney an oxidase nitrogen synthesis enzyme expression accentuate;High sterone Diet big rat in vivo of super oxygen ion increment, the super oxygen ion in the kidney also increases;An oxidase nitrogen and super oxygen ion occurrence respond born have a toxicity action to the cells of lead oxidize second nitrate.A series of research effect hints that the high sterone Diet cause kidney injure of possible mechanism BE:An oxidase nitrogen synthesis enzyme produce an oxidase nitrogen, and organize medium super oxygen ion occurrence with cystic kidney to respond, born have a toxicity action to kidneys cell of lead oxidize second nitrate, result in an apoptosis thus.An oxidase the nitrogen increase to relate to proteinuria, an oxidase nitrogen synthesis enzyme expression increment and one oxidase nitrogen of increase may through an apoptosis cause the glomerulus harden and renal tubule mesenchyme the cystic kidney injure.
They also discover in the research, use a the oxidase nitrogen synthesis depressant can prevent°from the shell membrane cytolysis of the glomerulus series and obstruct the occurrence of proteinuria, evolve and lower a glomerulus transforming growth factor, TGF the summation of expression and afterbirth outside stroma of the ? , prevent°from glomerulus sclerosis.
Gu Ru’s Han’s professor’s introduction say, this research not only confirmed further the high sterone Diet will cause the healthy person’s cystic kidney damaged, aggravate the nephrosis sufferer’s cystic kidney damage, also announced to public it some damage mechanisms.Though it is the report which starts experiment a research on animal’s body, has very great instruction action to clinically.In the clinical fulfillment, a lot of kidney patients are like nephrotic syndrome, chronic uremia and equal part of chronic nephritis suffererses have lipid mettabolic disorder.This has a certain relation with high sterone Diet.He emphasizes to point out, every have the patient of cystic kidney damage, must carry on declining a sterone treatment while appearing high lipemia, even want to control a Diet, injure according to the cystic kidney of the reason carry on Diet enzyme regulation.Generally speaking, the nephrosis sufferers all should as far as possible use a simple elegance Diet, eat the high sterone Diet less and this contains protection action towards defering cystic kidney damage.
Gu Ru Han professor point out, the modern living is wealthy, many families usually three meals big Hun big oil on the first, all has influence to the cardiac loop cerebral demulcent therapy, reconciliation kidney.Should pass publicity, let the crowd all know, the high sterone Diet will cause the cystic kidney injure this scientific knowledge, let people change a not scientific Diet habit possibly.
Aug
23
By: Gelais
In: Female physiology | Permalink
